In recent years, prescription of antilipemic drugs, particularly statins, has been marked by various controversies, calling into question the patients' beliefs as to the rationale, efficacy, and usefulness of these treatments. Doctors also face regular complaints from their patients, especially of the musculo-articular type, which the patients tend to assign too readily to their statin treatment. As a result, over the past years, there has been a growing number of patients who abandon their antilipemic treatment, at times without medical advice. The adverse reactions caused by the drugs, along with the implementation of such beliefs, are rather challenging to the doctor, and this to such an extent that some physicians feel that, nowadays, it takes courage to prescribe a statin therapy, while being confronted to this public counter belief. This article attempts to address these issues, while providing a reply to the most-commonly raised accusations.