Transplantation, chronic inflammatory bowel disease, and hepatic steatosis: highlights in 2023

Back
Géraldine Dahlqvist, Olivier Dewit, Nicolas Lanthier, Peter Stärkel Published in the journal : February 2024 Category : Hépato-gastroentérologie

Summary :

The year 2023 marked numerous developments and advances in the field of hepato-gastroenterology. The deleterious impact of frailty and sarcopenia on the prognosis of patients with cirrhosis, listed for transplantation, is clear. A care pathway that covers pre-transplant preparation and rehabilitation for up to two years after liver transplantation has been developed. It includes a full nutritional and functional assessment of patients and offers enhanced dietetic, physiotherapeutic, and psychosocial care. For inflammatory bowel diseases, two new drugs have emerged: risankizumab for Crohn's disease and upadacitinib for ulcerative colitis. Their benefits and significance relative to existing treatments are presented. Finally, a standardized nomenclature for steatotic liver disease (SLD) has been published and accepted by the scientific communities. The two main SLDs are alcohol-related liver disease (ALD) and metabolic dysfunction-associated steatotic liver disease (MASLD). Patients suffering from both diseases are classified as MetALD. This article reviews the diagnostic criteria for these common conditions.

Keywords

Transplantation, frailty, exercise, IBD, risankizumab, upadacitinib, steatotic liver disease (SLD), MASLD, MASH