HIV/AIDS has been transformed into a manageable, chronic condition and the life expectancy of patients living with human immunodeficiency virus (HIV) is now comparable to those without the disease. This is mainly due to the emergence of combination antiretroviral (cARV) therapy. This situation poses many new problems and challenges: persistent inflammation leading to immune activation, multi-morbidities, accumulation of toxicity of antiretroviral treatments, ageing and, finally, overloading of health systems especially in low resource countries. In this article we discuss many of these challenges.
HIV, ageing, heart, kidney, bone, neurocognitive impairement