An uncommon case of ectopic pregnancy: cornual pregnancy after salpingectomy

C. Bentin, F. Grandjean Published in the journal : December 2016 Category : Gynecology and Obstetrics

This is a case report describing an ectopic pregnancy occurring in the remnant stump following salpingectomy. A pregnancy implanted in this location appears very uncommon, thereby rendering the correct diagnosis challenging. This contribution comprises a case description, a presentation of the different diagnostic and therapeutic methods available to date, as well as a succinct literature review. We have also highlighted the requirement of performing salpingectomy by sectioning the isthmus of the uterine tube at the uterine horn, then coagulating the horn's intramural portion. Lastly, we have taken into consideration a series of practical recommendations.

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Rheumatology and dermatology

C. Peeters, C. Francès, F. Houssiau, M. Baeck Published in the journal : December 2016 Category : Dermatology

We report herein on the «PEAU’se dermatologique» meeting of the Cliniques Universitaires Saint-Luc held on February 15, 2016, and focused on dermatological and rheumatologic pathologies. Professor Camille Francès, head of the Dermatology department at Hôpital Tenon in Paris, presented the dermatological manifestations of lupus erythematosus and dermatomyositis. Professor Frédéric Houssiau, head of the Rheumatology department at the Cliniques Universitaires Saint-Luc, enlightened us on the brainteaser constituted by the auto-antibodies occurring in systemic rheumatisms.

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Clinical and biological presentation of primary hyperparathyroidism depending on vitamin D status

M. Yazidi, M. Chihaoui, F. Chaker, M. Feki, H. Slimane Published in the journal : December 2016 Category : Endocrinologie et diabétologie

Primary hyperparathyroidism (PHPT) and vitamin D deficiency are two common diseases. Their combination seems also to be common and might influence the clinical and biological expression of PHPT. Forty two patients with PHPT in whom vitamin D (25OHD) was measured at diagnosis were studied retrospectively. Vitamin D deficiency (plasma 25OHD<10ng/ml) was observed in 40,5% of PHPT patients. Osteopenia and osteoporosis were more frequent (p=0,01) and PTH level was higher (567,9±697,0 µg/l vs 259,8±198,8 µg/l p=0.04) in patients with vitamin D deficiency. Low plasma 25OHD levels may contribute to the severity of PHPT. Measurement of 25OHD should be routinely performed in PHPT patients to better assess the severity of the disease and to consider possibly vitamin supplementation.

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«We are all Charlie!» What are the cardiovascular consequences?

Christophe Scavée Published in the journal : November 2016 Category : GRAPA

Cardiovascular diseases remain the principal cause of natural death worldwide. Besides the standard risk factors, there is also stress, an undervalued source of cardiac events. Among the underlying causes of stress, there are natural disasters, as well as terrorism, with the latter having now reached Europe. A recent study revealed that, following the attacks at Charlie Hebdo in Paris, the number of both sudden deaths and hospitalizations for cardiovascular events abruptly rose. Similar statistics were observed in the US after the 2001 attacks in New-York, or in the aftermath of a major earthquake in Los Angeles. As a result, the harmful effects of stress must be better assessed in order to enable us to minimize its impact on the individuals’ health.

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Smoking cessation and cardiovascular prevention

Véronique Godding Published in the journal : November 2016 Category : GRAPA

Smoking cessation is the most efficient step for reducing cardiovascular risk in smokers. Stopping smoking is associated with a decreased risk of stroke and hypertension, in addition to improving patients' lipid and inflammatory profiles. It also lowers the risk of developing Type 2 diabetes, along with improved diabetes control and lowered risk of complications. Smoking cessation has been shown to improve physical fitness, in association with a more balanced diet. It is therefore crucial to pay attention to active and passive smoking in cardiovascular risk factor management by means of the 5A rule.

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Cholesterol and nutrition: Which dietary advices should we provide and for which impact?

Véronique Maindiaux Published in the journal : November 2016 Category : GRAPA

LDL-cholesterol is the major therapeutic target in the management of cardiovascular risk factors. Several dietary interventions showed significant improvements whilst lowering blood LDL-C levels, such as replacing atherogenic fats by unsaturated fats, eating plant sterols from enriched foods, increasing soluble fiber consumption, consuming unsalted nuts, and, at times reducing dietary cholesterol. When considered separately, each result seems modest. If we however associate the proposed dietary interventions, the results are cumulative, resulting in a greater impact on LDL-C levels that decrease by 20 to 30%. This is relevant for primary prevention and for target groups at the highest cardiovascular risk, thereby increasing the nutritional quality of the diet.

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Achieving glycaemic targets in primary cardiovascular prevention

Michel P. Hermans Published in the journal : November 2016 Category : GRAPA

For any diabetes type, glucose control aims to prevent microvascular complications. The speed of the β-cells' functional decline will guide the progressive or rapid initiation of lifestyle changes, supplemented by oral monotherapy, combination therapy, triple therapy (oral or injectable), and eventually basal or basal-prandial insulin administration. All currently marketed therapeutic classes can be used either alone or in combination, preference being given to medications with weight neutrality, free of hypoglycemic episodes, without deleterious effects on β-cells, and possibly with additional macrovascular benefits.

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Glycemic targets in primary cardiovascular prevention

Michel P. Hermans Published in the journal : November 2016 Category : GRAPA

Regardless of the diabetes type, glucose control aims to prevent microvascular complications. Besides acute metabolic decompensation settings, appreciation of this control is mainly based on determining past and current HbA1c levels while documenting the occurrence of hypoglycemia episodes. Recently, the Social Security has made available to Type 1 diabetes patients the continuous measurement of interstitial glucose by means of subcutaneous sensors. On account of this therapeutic advance, we have now to consider new statistics and glycemic targets based on ambulatory glucose profiles generated in this way, including the concept of time spent within the target area.

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Familial hypercholesterolemia

Olivier S. Descamps Published in the journal : November 2016 Category : GRAPA

Familial hypercholesterolemia (FH) is one of the most common fatal genetic diseases, affecting over 25,000 Belgians. It is responsible for very high cholesterol levels (> 300mg/dL) from birth, along with an increased risk of early vascular, cardiac, and cerebral complications, such as myocardial infarction and stroke, from the age of 30 years onwards in men and 40 in women. Cardiovascular complications may, however, be prevented by means of early diagnosis and proper treatment, ideally started in childhood.

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O.S. Descamps Published in the journal : November 2016 Category : GRAPA

A recent broadcast of the ARTE channel titled "Cholestérol: le grand bluff" was questioning one of the most solid pillar of cardiovascular prevention: the role of cholesterol in cardiovascular disease and the usefulness of the drugs lowering cholesterol to prevent this disease. It raised many reactions amongst our patients creating doubt on the justification of their treatment for their high cholesterol. To face such "denial" attitude, the Belgian Association of Patients with Familial Hypercholesterolemia (www.belchol.be) and the Belgian Society of Atherosclerosis (Belgian Society of Atherosclerosis) responded by sending a letter to the President and the Director of Arte as well as the Manager of the show. Louvain Medical reproduced here this letter.

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