We herein report on the “Peau’se dermatologique” meeting held on June 3rd, 2019 in the Cliniques universitaires Saint-Luc, Brussels, and focused on dermatological manifestations of systemic diseases. Professor Camille Francès, member of the Dermatology department at Hôpital Tenon in Paris, presented eight interesting clinical cases of systemic diseases with associated dermatological features.
Skin necrosis, aseptic abcess syndrome, IgG4-related disease, POEMS syndrome, H syndrome, Erdheim-Chester disease, ADA2 deficiency-related disorder
What is already known about the topic?
-The skin is a significant target organ of systemic diseases.
-It is essential to recognize the dermatological signs of these systemic diseases, which may facilitate diagnosis.
What does this article bring up for us?
- This article reviews the systemic diseases causing skin necrosis.
- It recalls the clinical features of several uncommon diseases with dermatological manifestations such as the POEMS syndrome and Erdheim-Chester disease.
- It provides more insights into three newly described systemic diseases: IgG4-related syndrome, H syndrome and ADA2-deficiency-related disorder.
- It redefines the concept of “aseptic abcess syndrome”