Dermatology and immuno-allergology

Diane Declaye (1), Olivier Aerts (2), Alexia Kervyn (3), Laurence de Montjoye (1), Laura Nobile (1), Didier Ebo (4), Marie Baeck (1) Published in the journal : July 2019 Category : Dermatology

Summary :

We report on the “PEAU’se dermatologique” meeting held on June 18, 2018, organized by the Dermatology department of the Cliniques universitaires Saint-Luc, which was focused on immuno-allergology. The first part of the meeting, presented by Professor Didier Ebo, Head of the Department of Immunology and Allergology at UZA (Universitair Ziekenhuis Antwerpen), addressed the problem of “Perioperative hypersensitivity reactions”. The second part, presented by Professor Olivier Aerts (UZA), was dedicated to "Atypical aspects of contact dermatitis".

Key Words

Perioperative, hypersensitivity reactions, drug allergy, anaphylaxy, tryptase, skin tests, curare, antibiotic, chlorexidin, latex, basophil activation test, specific IgEls

What is already known about the topic?

- Hypersensitivity reactions during or after a surgical procedure are relatively common, with an incidence ranging from 1/20 000 to 1/1361. They are unpredictable and can be life-threatening.

- In a recent prospective study, the incidence of perioperative reactions was 1/385 including 52% of anaphylaxis cases.

What does this article bring up for us?

- Recall the relevance of a good collaboration between surgeons, anesthetists, and dermato-allergists in case of hypersensitivity reactions, as well as the relevance of skin tests.

- Recall the need for a tryptase assay in the immediate aftermath of a hypersensitivity reaction. -Contact dermatitis can bear disconcerting clinical features. It is essential to suspect this condition when confronted with a resistance to properly-conducted treatments.