Cytomegalovirus infection associated with portal vein thrombosis and thrombocytopenia: a case report

Gianfranco Di Prinzio (1), Phung Nguyen Ung (2), Anne-Sophie Valschaerts (2), Olivier Borgniet (2) Published in the journal : April 2018 Category : Internal Medicine

Summary :

We here present the case of portal vein thrombosis in a patient exhibiting symptoms of cytomegalovirus infection, confirmed by serology and polymerase chain reaction (PCR) and complicated by thrombocytopenia. The literature reveals growing evidence that human CMV likely plays a role in thrombotic disorders. However, only 11 cases of CMV-induced visceral venous thrombosis have been described so far. On the other hand, thrombocytopenia is a well-known complication of CMV infection. The patient was successfully treated using high-dose immunoglobulins by intravenous route.

Key words

Venous thrombosis, portal vein thrombosis, purpura, viral infection, thrombocytopenia, intravenous immunoglobulins