The exposome, climate change, and health

Introduced by Chris Wild in 2005, the concept of the exposome refers to the totality of exposures experienced by an individual or population over a lifetime. In recent years, various contributions have enriched this concept, earning it a central place in the field of environment and health. Advances in analytical chemistry, toxicology, epidemiology, systems biology, modeling, social sciences, and environmental sciences have helped to better define the objectives of exposome research and the methods and tools used to explore it. Climate change is essentially reflected by a transformation of the exposome. This perspective is valuable from a prevention standpoint: on the one hand, our health in 25 years strongly depends on our current and future exposures; on the other hand, these exposures are modifiable by nature, which highlights our collective and individual responsibility.