The antiphospholipid syndrome is an acquired autoimmune thrombotic disorder that has been known since 1906, with an incidence of 40 to 50/100,000 people. Its complex pathophysiology remains poorly understood at present, with all organs potentially affected. Symptoms are very variable and most commonly associated with multiple thrombotic or thromboembolic events. If such manifestations including obstetric events occur in young patients, we should consider the diagnosis of antiphospholipid syndrome. Owing to its morbidity and mortality, this syndrome constitutes a diagnostic and therapeutic emergency.
What is already known about the topic?
The antiphospholipid antibody syndrome (APS) is a disease with a complex pathophysiology. In clinical practice, the great variability of its clinical presentations renders its diagnosis difficult. However, the APS diagnosis is essential in order to prevent the significant morbidity and mortality associated with this syndrome.
What does this article bring up for us?
Based on a clinical case, this article nicely illustrates the atypical and multifocal character of the thrombotic events occurring in APS. We similarly recall the diagnostic criteria in view of evoking and confirming the APS presence.
Antiphospholipid antibodies, arterial and venous thromboses, atypical presentation